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Sodium Imbalance: Causes, Symptoms, and How Medications Affect Your Levels

When your body’s sodium imbalance, a condition where blood sodium levels are too low or too high, disrupting nerve and muscle function. Also known as electrolyte disorder, it’s not just about salt cravings—it’s about how your kidneys, heart, and meds work together to keep you balanced. Sodium isn’t just table salt. It’s the key player in keeping your cells hydrated, your nerves firing, and your muscles contracting. Too little (hyponatremia, a sodium level below 135 mEq/L, often caused by overhydration, diuretics, or heart failure) or too much (hypernatremia, a sodium level above 145 mEq/L, usually from dehydration or kidney issues) can turn everyday life into a health risk.

Many common medications directly mess with sodium levels. Diuretics like hydrochlorothiazide flush out sodium—and sometimes too much. Antidepressants, especially SSRIs, can trigger a condition called SIADH, where your body holds onto water and dilutes sodium. Even pain meds like NSAIDs and some antibiotics can interfere with kidney function, leading to unexpected drops. If you’re on multiple prescriptions, especially for high blood pressure, depression, or chronic pain, your sodium might be quietly drifting out of range. And it’s not always obvious. Fatigue, nausea, headaches, or confusion? Could be your sodium, not just stress or aging.

What’s surprising is how often this gets missed. Doctors check potassium and glucose—but sodium? Not always. Yet it’s one of the most common lab abnormalities in hospitalized patients. The good news? Fixing it often means adjusting meds, tweaking fluid intake, or treating the root cause—not just popping a salt pill. If you’ve had recent surgery, started a new drug, or feel off without a clear reason, ask for a basic electrolyte panel. It’s quick, cheap, and could explain a lot.

The posts below dive into real-world cases where medications, aging, and lifestyle choices collide with your body’s sodium balance. You’ll find guides on how certain drugs like diuretics, antidepressants, and even over-the-counter painkillers can tip the scales. You’ll learn what symptoms to watch for, how to talk to your doctor about testing, and what to avoid when you’re managing multiple conditions. No fluff. Just what actually matters when your sodium’s out of whack.

Hyponatremia and Hypernatremia in Kidney Disease: What You Need to Know

Hyponatremia and hypernatremia are common, dangerous complications in kidney disease. Learn how fluid balance, diet, and medications affect sodium levels-and what you can do to stay safe.